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The limited human evidence includes: A randomised double-blind placebo-controlled Phase 2 enema trial in ulcerative colitis with 53 participants, published only as a meeting abstract

It was one of the very first dermal fillers to receive FDA approval for safety and efficacy, and has one of the longest histories of continuous and safe use, at over a decade of continuous use

Injection site reactions represent another category of commonly observed side effects, though these are typically mild and self-limiting

Medically reviewed by: Jayden Lee, PharmD, EMBA Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes

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