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Results At 1 year, patients achieved significant weight loss with a median total weight loss (%TWL) of 25.5% and a median excess weight loss (%EWL) of 66.3% compared to 16.6% and 40.8%, respectively, at treatment initiation with BMI reduction of 3.7 kg/m 2

Extended-release capsules (Topamax XR) are also available in strengths ranging from 25mg to 200mg for sustained effects

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Older Adults (50+) : May need to use the standard or advanced doses of GHSs (Sermorelin, Ipamorelin ) to achieve the same GH pulse that a younger person gets from a beginner dose