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Oral semaglutide is co-formulated with the absorption enhancer sodium N -(8-[2-hydroxybenzoyl]amino) caprylate, which facilitates the transcellular absorption of semaglutide across the gastric mucosa [2]
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The lack of balance between the production of ROS and the antioxidant defense system of animals will lead to DNA hydroxylation, protein denaturation, lipid peroxidation, cell apoptosis, ultimately lead to cell damage (Yang et al., 2016)
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