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Risk ratios (RR) for MACE estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons
Its FDA-approved for weight loss and still being studied for diabetes
This is very similar to how other GLP-1 medications like semaglutide and tirzepatide are taken
2.8 Sensitivity analyses Deterministic sensitivity analyses (DSA) were conducted to assess the impact of parameter uncertainty on model outcomes by varying one parameter at a time while holding all others constant
J Biol Chem, 1966
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