is semaglutide hard on your liver How do GLP-1 weight loss drugs affect the liver? Semaglutide as a MASH Treatment:

Similarly, genes involved in cell cycle regulation and ECM organization, including those in the collagen biosynthesis and modifying enzymes pathway (ADAM metallopeptidase domain 12 ( Adam12) , laminin subunit beta 3 ( Lamb3 ), collagen type VI alpha 3 ( Col6a3 ), neurocan ( Ncan ) and integrin alpha 6 ( Itga6 )) also exhibited reduced expression

12 , a036392 (2020)

Some people experience a weight loss plateau on GLP-1 medications

Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know

There have been Studies which indicate causation of Ozempic and a greater risk of gallbladder disease or gallstones