A 2019 RCT found 0.5% bakuchiol comparable to 0.5% retinol for wrinkle and pigmentation outcomes with less scaling
2011 Lancet) The combination is more effective than either drug alone at lower doses, and the lower doses reduce side effects of both components
Eliasson MJ, Huang Z, Ferrante RJ, Sasamata M, Molliver ME, Snyder SH, et al
GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids
132 Vives-BauzaC.ZhouC.HuangY.CuiM.de VriesR