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7 However, a letter to the editor showed that, had the meta-analysis included trials for off-market GLP-1RAs, which still represent valuable data, the association would not have been significant

Skipping steps or escalating too quickly is the most common cause of intolerable symptoms and of early discontinuation

Accordingly, grant at least a few months washout period or preferably administer the cycle only annually

Much of this increase is explained by changes in diagnostic practice, including: Broadening the definition of ASD to include higher-functioning children Increased accuracy in the diagnosis of ASD (particularly for children who previously may have been diagnosed with intellectual disability) Increased awareness of the disorder Earlier identification of young children However, we cannot rule out that there is a true increase in the risk for ASD

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