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Vitamin B 12 deficiency has been observed in between 40% and 80% of the vegetarian population who do not also take a vitamin B 12 supplement or consume vitamin-fortified food

What about B12 shots for energy or weight loss

The cycle structure exists for a practical reason: continuous stimulation of the same receptor pathways can lead to reduced sensitivity over time, and a rest period allows the system to reset before the next cycle produces full effect

Whether someone with PA can utilize liver stores is something I'm not sure about - some textbooks indicate that the mobilization mechanism of B12 from the liver is not well understood

Panesar NS (1999)