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Clinically 1 , IGF-1 signalling activates Akt/mTOR, the central switch for translating exercise and nutrition into muscle protein accretion and performance gains

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Administration frequency varies based on deficiency severity and individual response

Supporting Factors These inputs support tissue synthesis, collagen cross-linking, matrix hydration, copper balance, and overnight repair: Optional adjuncts: red-light therapy (630670 nm) for 1020 minutes daily, and microneedling every three to four weeks during Phase 2