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doi: 10.3390/cells10051056 56 SeetBTDikicIZhouMMPawsonT

In rat insulinoma cell line INS-1E, a high concentration of glucose (16mM) not only inhibits the activity of the K ATP channel but also reduces the concentration of H 2 S, meanwhile H 2 S supplementation can activate the K ATP channel (56)

The signal obtained for the quantifier product ion was converted to a concentration with the help of a standard calibration curve

5o, p, r S2), indicating that GSH inhibited high glucose-induced PSC activation