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Those criteria exist because the trials that earned approval enrolled patients who met them

This makes it easy to follow the prescribed schedule and ensures safe and accurate dosing

Medicaid coverage varies by state

Given that DPP-4 clearly plays a role in the clearance of a number of hormones involved in the regulation of glucose homeostasis, the question arises of whether changes in DPP-4 activity might play a role in the pathogenesis of T2DM