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In cell-based and biochemical laboratory research, GHK-Cu has been investigated for its copper-binding behaviour and, in preclinical models, for associations with pathways relating to gene expression, extracellular matrix turnover and oxidative-stress responses
It gets its scant nutrition from synovial fluid (the joint's natural lubricant)
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Maniakas A, Henderson YC, Hei H, Peng S, Chen Y, Jiang Y, Ji S, Cardenas M, Chiu Y, Bell D, Williams MD, Hofmann MC, Scherer SE, Wheeler DA, Busaidy NL, Dadu R, Wang JR, Cabanillas ME, Zafereo ME , Johnson FM, Lai SY
10 As noted in a November 2017 paper in Free Radical Biology and Medicine: 11 "Epigenetics is a rapidly growing field that studies gene expression modifications not involving changes in the DNA sequence
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