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Common adverse effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea), decreased appetite, and hypoglycaemia when combined with insulin or sulphonylureas
Additionally, GLP-2 increases the barrier function of the gut epithelium and regulates gastric motility, gastric acid secretion, and intestinal hexose transport [66, 67]
This could be positive news for people suffering from these conditions, as a new MDL could be formed
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The introduction of three distinct receptor pathways alters the tolerability and safety characteristics of the drug: Gastrointestinal Tolerance (The Same, Yet Better) : Because both drugs feature a strong GLP-1 backbone, nausea, vomiting, diarrhea, and constipation remain the most common side effects
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