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Data shows that urinary ferritin is closely linked to tubular injury, and it often rises earlier than the appearance of proteinuria
Previous studies have also reported carnitine deficiency in patients taking valproic acid and having a multiple ASM regimen (13, 15, 19)
Monitoring Schedule: Initial phase: Weekly or monthly monitoring Maintenance phase: Periodic monitoring (e.g., every 3-6 months) By watching these lab results and making dosage changes as needed, doctors can tailor B12 therapy for each patient
J Inherit.Metab Dis 2008;31(4):503-507
IGF-1 is a surrogate marker : a laboratory value that stands in for a hoped-for outcome
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