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As of 2024, over 2% of Americans use GLP-1s for overweight/obesity, and around 4% use them overall (for any indication), with nearly half of users using them for weight loss

[1] [3] Understanding these multisystem effects is essential when evaluating potential adverse effects, including fatigue, as the widespread distribution of GLP-1 receptors means these medications influence numerous physiological processes beyond glucose metabolism

Freeman and Company, 2019

Semaglutide yes, the active ingredient behind the FDA-approved weight loss medications that have taken the world by storm is a lab-engineered peptide modeled after Glucagon-Like Peptide-1

What matters is consistency from week to week