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It is found in the cytosol and nucleus and has been linked to protein kinase C- signaling [30] and iron homeostasis [31]
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For instance, hydrogen sulfide exposure may result in a decreased activity of APS reductase and a depressed sulfate uptake
This mitochondrial failure is the direct biochemical driver of the profound, debilitating fatigue and post-exertional malaise (PEM) that patients experience after even minor physical or cognitive exertion
Interplay Between Insulin Resistance and Immune Dysregulation in Type 2 Diabetes Mellitus: Implications for Therapeutic Interventions
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