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It generally continues unchanged during the switch because it works through an entirely different mechanism (reducing hepatic glucose production) and does not interact with incretin receptors

Int J Mol Sci (2021) 22(14):7475

Orlistats gastrointestinal effects are often the most disruptive to daily life

Summary: You can take weight loss injections on a plane when accompanied by valid prescriptions, appropriate documentation, and proper storage in hand luggage