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Ferroptosis, a recently discovered iron-dependent form of nonapoptotic cell death, has been associated with neurodegeneration and p53-mediated tumour suppression 28,29
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Diabetes 57: 2280-2287, 2008
Both agents affect glucose homeostasis, albeit differently
The BENDIP study demonstrated that neuropathic symptoms, measured using the NIS as the primary endpoint, improved after 6 weeks of treatment with benfotiamine at a dose of 300 mg twice daily (no improvement was observed with 300 mg once daily) [71]
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