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Description

Intestinal absorption of carnitine and its renal reabsorption are mainly mediated by the plasma membrane organic cation transporter 2 (OCTN2SLC22A5), which has the highest affinity for carnitine among the carnitine handling transporters

NEJM March 18,2021 vol 384 no 11

Nat Rev Gastroenterol Hepatol 13 , 196205, (2016)

EST), with limited weekend support

569 Their chemical structure, dosage form, and administration route are the main determinants of their absorption, distribution, metabolism, and excretion, thereby affecting their efficacy and safety