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Davies LC, Jenkins SJ, Allen JE, et al
doi: 10.1016/s0304-3835(01)00797-2 72 XinHDengYCaoJ
however, in later cancer stages, those mutations drive persistent downregulation of SQOR, resulting in excess H 2 S accumulation that promotes tumor growth and metastasis
The review addresses translational challenges including workflow constraints, lack of standardization, limited external validation, and cost-effectiveness issues, positioning multi-omics biomarkers within clinically defensible scenarios, such as recurrent implantation failure with euploid embryos and embryo selection under discordant morphological signals, where integration may add actionable value
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