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Reduced appetite while therapeutically intended, this can occasionally lead to inadequate nutritional intake Injection site reactions mild redness, bruising, or discomfort at the site of subcutaneous injection Fatigue and dizziness reported in a subset of trial participants, often associated with early treatment phases Hypoglycaemia (low blood sugar) uncommon with retatrutide alone, but the risk increases when it is used alongside insulin or sulfonylureas

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Studies have found that IGF-1 LR3 also helps lower inflammation in joints, alleviating discomfort and promoting faster recovery after physical strain or injury

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