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Acknowledgements We thank the laboratory technicians in our animal unit at Novo Nordisk (Mlv, Denmark) for daily caretaking and for overseeing our experiments

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Oral administration follows a ramping protocol: 250 micrograms daily for the first three weeks, increasing to 500 micrograms for maintenance

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The content is not intended to encourage application, diagnosis, or self-treatment of unlicensed individuals, and should not be used as a substitute for the clinical judgment of a qualified healthcare provider