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GSH depletion is strongly associated with impaired immune function and with disease development including viral diseases, cancer, cardiovascular diseases, arthritis and diabetes (Sinha et al., 2018
Repurposing metformin: an old drug with new tricks in its binding pockets
In this review, we first introduce metabolic pathways that enable glutamine to respond to diverse cellular needs and then discuss the metabolic link by which glutamine-derived metabolites may affect cellular metabolic processes, including NEAA synthesis, epigenetic modifications, and hypoxia adaptation
Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis
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