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53 ) (Supplementary Data Table 1)

Week 1-4: 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12 (if needed): 1 mg once weekly, if further glycemic control is required Week 13 onwards (if needed): 2 mg once weekly, if your body can tolerate the previous dosage and further glycemic control is required This medication is started at 0.25 mg per week until you reach the maintenance dose

While SAMe is naturally produced by the body, additional supplementation is often recommended for pets in need of extra support for liver function