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While a direct link between excess iron and optic neuropathies is not established, iron's ability to produce highly reactive ROS may play a role in its pathogenesis

For weight management specifically, lifestyle modification remains foundational, incorporating medical nutrition therapy, structured physical activity programs, and behavioral counseling

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The UK clinical guidance is clear: stop the medication at least one month before trying to conceive, use reliable contraception while taking it, and contact your prescriber if you become pregnant unexpectedly