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Novo Nordisk maintains originator exclusivity but faces mounting pressure from Eli Lilly whose tirzepatide has demonstrated statistically significant advantages in both HbA1c reduction and weight loss in pivotal trials like SURPASS two
Furthermore, Protein Atlas indicates that GLP-1 receptor protein (but not mRNA) is present in skeletal muscle, whilst conversely GLP-1 receptor mRNA (but not protein) is detected in adipose tissue
It may arise de novo or in a pre-existing mole
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If the provider states or implies the condition is due to another cause (e.g., neuropathy due to chemotherapy), the linkage to diabetes cannot be assumed
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