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PT-141 , Bremelanotide , was derived directly from MT-II through C-terminal amide hydrolysis, producing a compound that retains the cyclic heptapeptide structure and MC3R/MC4R pro-sexual activity while reducing MC1R-mediated tanning

Theyre primarily prescribed for diabetes and weight loss in people with obesity

Obesity is associated with reduced sperm quality including lower counts, impaired motility, and increased DNA fragmentation

Cost: The list price of Zepbound is $1,086.37 a month, but people with commercial insurance that covers it may pay $25 for a one- or three-month prescription, and people with insurance that doesnt cover it may be eligible to pay as little as $650 a month

Phase 3 Goal: Reach a therapeutic dose that supports steady, sustainable weight loss