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Patients considering phentermine-semaglutide combination therapy should also undergo genetic testing to understand their baseline metabolic risk
Premenopausal women with functioning ovaries typically have enough estrogen production to compensate for the loss from adipose tissue, though exceptions exist, especially with very rapid or very significant weight loss
It can be administered in a wide variety of ways as well, but breathing it in via a nebulizer or having intravenous injections are the ideal route
Taking both increases the chance of serious side effects
In the four-year Wegovy trial, 16.6% of participants who received Wegovy (1,461 people) experienced an adverse event that led to them permanently discontinuing their use of the medication
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