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Other approved options include orlistat (available over the counter as Alli or on prescription as Xenical) and liraglutide (Saxenda), though the latter has become less commonly prescribed since the availability of semaglutide and tirzepatide
At six months, people taking bupropion were 15-20% less likely to gain a clinically significant amount of weight (5% or more of their baseline) than those taking sertraline, the most commonly prescribed antidepressant.1 Some bupropion users actually lost a small amount, about half a pound on average at six months, though this reversed to a modest 1.2-pound gain by 24 months
Barrett AW, Scully C
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