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Patients should be monitored for serious adverse events including pancreatitis (severe abdominal pain radiating to the back, with or without vomiting), gallbladder disease, acute kidney injury (particularly with dehydration from persistent GI symptoms), diabetic retinopathy complications (with Ozempic/Rybelsus), and hypoglycemia (especially when used with insulin or sulfonylureas)
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The medicine is also famous for its off-label use in treating obesity and promoting weight loss in overweight individuals
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