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Similar to the PL and IL for Irs2 , chronic alcohol drinking also decreased CA1 Irs2 levels in both male and female msPs, further highlighting the possible role of this gene in alcohol-related cognitive behavior
[3] In humans, defects in GSS are inherited in an autosomal recessive way and are the cause of severe metabolic acidosis, 5-oxoprolinuria, increased rate of haemolysis, and defective function of the central nervous system
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