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For example, a 2015 study found that patients with chronic fatigue syndrome responded favorably to vitamin B12 injections in combination with folic acid supplements

Discussing B12 Shots & Injections: Highlighting Concerns Surrounding Cyanocobalamin unhealthy Potential Negative Health Effects

It took several weeks before I was able to bicycle (a favourite Dutch hobby) more than a few kilometres, but nowadays, I only have faint memories of how sick I really was

TB500: Usually given as a shot under the skin or into the muscle

People with low B12 may experience: Persistent fatigue or low energy Weakness Brain fog, concentration issues, or memory changes Low mood or irritability Pins and needles, numbness, or nerve-type sensations Mouth ulcers or a sore tongue Paleness or shortness of breath (if anaemia is present) Some symptoms can become more serious if deficiency is prolonged, particularly neurological symptoms