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Source: Arrone, et al New England J of Medicine May 11, 2025 Researchers randomized about 1,500 people with obesity and without diabetes to be treated with either tirzepatide or semaglutide, both at the highest tolerable recommended doses, and followed them for 72 weeks
For now, physicians view MB as a precision tool for mitochondrial and skin support promising but not a pancea
For example, the FDA has reported that some compounded semaglutide products might contain semaglutide salts (semaglutide acetate and semaglutide sodium) instead of semaglutide base, which is present in FDA-approved branded medications
It is banned at all times for athletes under WADA oversight
Rybelsus is also expensive without coverage and is usually only approved for diabetes
