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It has been shown to skew the production away from the darker eumelanin and toward the lighter pheomelanin
candidate agents such as lycopene and melatonin have been confirmed to simultaneously alleviate inflammatory injury and oxidative stress responses in animal models via signaling networks like NF-B/MAPK and Nrf2 (210, 211)
doi:10.1097/00001622-200103000-00008
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