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(2015) trial showed that high-dose oral supplementation (1,000 mg/day) did increase blood glutathione levels over 6 months, but the effect was far smaller than parenteral routes
Recent investigations have focused more on combination therapies, particularly pairing glutathione with its precursors (l-cystine, cysteine peptides) or other antioxidants (vitamin C, alpha-lipoic acid, zinc), reflecting the understanding that synergistic effects may enhance skin-lightening outcomes
Aging Pathobiol
Laut Badenhorst et al
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