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1973 Apr;81(4):557-67
Abstract Changes in lifestyle induce an increase in patients with hyperuricemia (HUA), leading to gout, gouty arthritis, renal damage, and cardiovascular injury
PMID: 6548970
However, increasing oral supplement doses (within safe limits) while awaiting medical review is generally considered safe, as B12 has very low toxicity and excess is excreted through the kidneys
In animal models, MSM has been shown to bolster the antioxidative capacity of cells compared to placebo controls, suggesting the presence of protective physiological pathways
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