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Common Side Effects Most people who take GLP-1 medications experience mild digestive symptoms that often improve over time: Nausea: The most frequently reported side effect Diarrhea: Usually temporary as your body adjusts Stomach upset: Can be reduced by eating smaller meals Loss of appetite: This is actually part of how the medication works Serious but Rare Side Effects Some side effects are uncommon but require immediate medical attention: Thyroid tumors: Reported in less than 1 percent of patients Gallbladder problems: Including gallstones in some patients Severe stomach pain: Could indicate pancreatitis Kidney problems: Especially if you become dehydrated Patients should discuss all potential risks with their healthcare provider before starting any GLP-1 medication
When to discuss changes with your provider Contact your provider about dosing frequency if any of these apply: You have been on the same dose and frequency for 3+ months with no weight change Side effects are persistent and significantly affecting quality of life You want to transition from daily to less frequent dosing You have reached your weight loss goal and want to discuss maintenance You are switching between different GLP-1 formulations The process of switching between GLP-1 medications involves careful dose conversion and may require restarting titration
On a tough day, you can pull out a portion of shredded chicken to toss with some jarred salsa, or microwave a serving of meatballs
It comes in two forms: tablet or liquid solution
JAMA Psychiatry 81 , 955956 (2024)
