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Patients with severe kidney disease or end-stage renal disease may not be appropriate candidates for this therapy, particularly if they have significant fluid retention or are prone to dehydration

Why the spread from few weeks to few months

At least one early trial funded by Wegovy and Ozempic manufacturer Novo Nordisk found that the drugs were successful: nearly half of teens in the trial achieved a healthy weight in about 17 months

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It is an active, deeply regulated physiological process involving hormones, neurotransmitters, and neural networks across the brain