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In fact, one study found that peoples bodies absorbed about 49% of a 1-mcg dose of cyanocobalamin, compared to 44% of the same dose of methylcobalamin ( Conversely, another study comparing the two forms reported that about three times as much cyanocobalamin was excreted through urine, indicating that methylcobalamin may be retained better within your body ( However, some research suggests that differences in bioavailability between the two forms may be insignificant and that absorption could be influenced by factors such as age and genetics ( Unfortunately, recent research directly comparing these two forms of vitamin B12 is limited

Moreover, over the last couple of decades, Americans have been eating larger portion sizes, relying on fast food and drinking sugary beverages such as sodas, smoothies, juices and energy drinks

10.1002/pmic.201500405 42 MccarthyM

A few notable mechanisms include improving insulin secretion, suppressing appetite, and delaying gastric emptying