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AUC and maximum z-scores were significantly increased during cocaine seeking compared to baseline in VTA dopamine neurons of vehicle-treated rats

Semaglutide and tirzepatide lead to 1520% weight loss, but surgery averages 2535% with longer durability

They slow digestion, reduce appetite, and improve glucose regulation, making it easier to lose weight steadily

The oral formulation, while still in various stages of availability through compounding pharmacies, offers an alternative for individuals who may prefer not to use injections

Diabetes prescriptions may be more stable and predictable, while obesity-related prescriptions can involve more frequent dose adjustments, therapy initiation, and discontinuation