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Results LPL treated with deoxycholate prevents formation of inactive helices To generate a homogenous sample of active LPL for cryoEM, we needed to disrupt the inactive LPL helices that form at high protein concentrations
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It sits embedded in the membrane, coiled through the lipid bilayer seven times, and it does nothing until a specific peptide arrives
PMID: 46 ZhangZZhangQTanYChenYZhouXLiuSet al
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