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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity

Ongoing research continues to evaluate the role of these agents in populations without diabetes, particularly in the context of obesity and primary cardiovascular prevention, suggesting that their therapeutic reach may expand further in the coming years

However, as suggested by a previous MR study [23], uric acid is downstream of l-carnitine, i.e., a mediator, so we did not exclude it as an invalid genetic instrument

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