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326 Within this context, activation of TLRs in macrophages deficient in mitogen-activated protein kinase kinase kinase 8 (MAP3K8, also known as COT or Tpl-2) leads to reduced phosphorylation of eukaryotic elongation factor 2 kinase (eEF2K), suggesting a pivotal role for MAP3K8 in regulating translation elongation
Certain fungi produce mycotoxins that can harm human cells, in part by interrupting the expression of genes responsible for glutathione production
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There were no serious adverse events reported during the trial
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