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Adverse effect screening: Changes in appetite, mood, energy, water retention, or joint symptoms are discussed

Binding at this receptor triggers intracellular calcium signaling cascades in somatotroph cells of the anterior pituitary, leading to growth hormone release in a pulsatile pattern that mimics physiological secretion in animal models

Song et al., 2023

Source: DailyMed (Contrave), DailyMed (Wegovy) Contrave and Wegovy drug interactions Contrave has a longer list of medications it can interact with than Wegovy