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Don't forget the essentials GHK-Cu (Glycyl-L-Histidyl-L-Lysine, Cu2+ copper complex) is a tripeptide of 340 Da free, 403 Da complexed with copper, discovered by Loren Pickart in 1973 at the University of San Francisco

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If your cardiovascular markers haven't budged despite months of supplementing, the dose, the quality, and what's actually inside the capsule are almost certainly the problem

(A placebo is not a control)

For people with genetic variants that cause more of an impact on CYP1B1 upregulation combined with an inability to eliminate the estrogen metabolites fast enough (due to phase II genes, diet, and lifestyle) then cigarette smoking is going to significantly increase the bad estrogen metabolites