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My honest read for most people walking in for skin and hair is start topical, and add a supervised injectable only when the goal is systemic recovery and after we rule out the reasons someone lands in the group of who should avoid peptides

Compared to classical gastroprotective peptides such as sucralfate or proton pump inhibitors (PPIs), it acts via a completely different pathway: restoration of mucosal microcirculation rather than acid reduction or formation of a mechanical protective layer

Its mechanism is purely metabolic: it directly targets lipid metabolism via inhibition of NNMT and restoration of cellular NAD+

PMC12313605 Staresinic, M., et al