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PMID 18057338

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Xenobiotics containing a carboxyl group (COOH) are widely used as drugs (for example simvastatin, valproic acid, or acetylsalicylic acid), herbicides, insecticides, and food preservatives

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Whether these effects add together, overlap, or interfere when the compounds are combined has not been characterized

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Abdullah Z, Cui Y, Platt RW, Renoux C, Azoulay L, Xia C, et al

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We propose once-daily dosing with tentative pre-exercise timing, though exercises impact on UA pharmacokinetics requires further investigation

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