Paravicini TM, Touyz RM
When catalyzed by GST, the prodrug releases cytotoxic compounds
symptoms occur during the neonatal period, infancy, or early childhood, as well as during adolescence and adulthood
If you experience initial shedding (increased hair fall in the first 2-4 weeks), this may actually indicate follicles transitioning from telogen (resting) to anagen (growth) phase
The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)