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Using an HCT116 5FUCRISPR screen, in which cells infected with the Gecko v1 library were cultured with or without 5FU for 11 days (Fig

Similarly, NO seems to influence skeletal muscle function through effects on excitation-contraction coupling, myofibrillar function, perfusion, and metabolism

Initial loading phases build reserves, while maintenance phases sustain benefits

In skeletal muscle specifically, MOTS-c has been shown to enhance glucose transporter-4 (GLUT4) translocation to the cell surface, the molecular mechanism by which muscle cells absorb glucose from the bloodstream

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