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Neurological disorders: Some neurological disorders result in constipation, especially those where the autonomic nervous system behaves irregularly

Int J Mol Sci 22(12):6352 Ogawa K, Yagi T, Guo T, Takeda K, Ohguchi H, Koyama H, Aotani D, Imaeda K, Kataoka H, Tanaka T (2020) Pemafibrate, a selective PPAR modulator, and fenofibrate suppress microglial activation through distinct PPAR and SIRT1-dependent pathways

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82 UA was observed to reduce reactive oxygen species (ROS) and interleukin-6 (IL-6) production in macrophages while enhancing fatty acid oxidation (FAO) under inflammatory and hypoxic conditions in vitro